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Effect of Diabetes on Brain Diseases

Diabetes mellitus affects the entire body, including the brains.Recent research suggests diabetes mellitus (DM) slows mental function and increase the risk of Alzheimer’s disease.Complications that occur in the brains is just one reason why we should control diabetes.

Scientists still unclear how type 2 diabetes affects the brains and there are many factors involved.

“High blood sugar may have a direct effect on nerve cells or cells in the nervous system suport. It may also damage the blood vessels large and small concerns. Other result is a diminished supply of oxygen to the brains that the risk of stroke,” said Alan Jacobson, professor emeritus of psychiatry at Harvard Medical School.

Diabetes begins with insulin resistance, in which fat, muscle and liver cells are unable to use insulin. Initially the reaction was pancreas responds by pumping more insulin.

Same enzyme that breaks down a protein called insulin also break beta-amyloid, which is abnormally formed in the brains of Alzheimer patients. More and more enzymes that break down insulin acts, the greater the accumulation of beta-amyloid.

Studies conducted in Sweden found an increased risk of Alzheimer’s disease in people with diabetes in middle age. Risk of Alzheimer’s disease in people with diabetes at the age of 65 is smaller.

“The longer you have diabetes, the higher the risk of Alzheimer’s disease,” said Margaret Gatz, professor of psychology at the University of Southern California, USA.

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